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primary antibodies against irs 2  (MedChemExpress)


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    MedChemExpress primary antibodies against irs 2
    Primary Antibodies Against Irs 2, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/primary+antibodies+against+irs+2/IRS2+Antibody/pm41243335-131-0-8
    Average 93 stars, based on 1 article reviews
    primary antibodies against irs 2 - by Bioz Stars, 2026-10
    93/100 stars

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    other:

    Article Title: Rutin inhibits hepatic gluconeogenesis and increases glycogen synthesis through the IRS/PI3K/akt signaling pathway in insulin resistant hepatocytes.
    Article Snippet: Rutin, a dietary flavonoid, can relieve insulin resistance to improve hyperglycemia, while the precise mechanism remains unclear.. In this study, we found that rutin bound well to the insulin receptor, alleviated glucosamine-induced insulin resistance in HepG2 cells and observably increased glucose consumption and glucose uptake in vitro.. Furthermore, rutin increased the levels of IRS-1, IRS-2, PI3K, p-AKT, p-GSK3β and p-FOXO1 and decreased the expression of p-IRS-1, p-GS, PEPCK and G6Pase, indicating that rutin could promote glycogen synthesis and inhibit gluconeogenesis via the IRS/PI3K/Akt signaling pathway.



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    Light micrographs of portions of human gingival biopsies submitted to immunohistochemistry for IRS detection and counterstained with hematoxylin. Light micrographs of human gingiva showing portions of the lamina propria from T2DM_poorlyC_P ( A ), T2DM_wellC_P ( B ), T2DM_without_P ( C ), Periodontitis ( D ), and Control ( E ) groups. The sections were subjected to immunohistochemistry for the detection <t>of</t> <t>IRS-2</t> (brown-yellow color) and counterstained with hematoxylin. Arrows: inflammatory cells; Fb: fibroblasts; BV: blood vessel. Scale bars: 20 µm. Figure ( F ): number of IRS-2-immunolabelled cells in the lamina propria of human gingiva biopsies.
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    Light micrographs of portions of human gingival biopsies submitted to immunohistochemistry for IRS detection and counterstained with hematoxylin. Light micrographs of human gingiva showing portions of the lamina propria from T2DM_poorlyC_P ( A ), T2DM_wellC_P ( B ), T2DM_without_P ( C ), Periodontitis ( D ), and Control ( E ) groups. The sections were subjected to immunohistochemistry for the detection of IRS-2 (brown-yellow color) and counterstained with hematoxylin. Arrows: inflammatory cells; Fb: fibroblasts; BV: blood vessel. Scale bars: 20 µm. Figure ( F ): number of IRS-2-immunolabelled cells in the lamina propria of human gingiva biopsies.

    Journal: Biomedicines

    Article Title: Longitudinal Study of the Influence of Periodontal Treatment on the Levels of Insulin Receptor Substrate-2 and Superoxide Dismutase 1 in Individuals with Type 2 Diabetes Mellitus

    doi: 10.3390/biomedicines14040742

    Figure Lengend Snippet: Light micrographs of portions of human gingival biopsies submitted to immunohistochemistry for IRS detection and counterstained with hematoxylin. Light micrographs of human gingiva showing portions of the lamina propria from T2DM_poorlyC_P ( A ), T2DM_wellC_P ( B ), T2DM_without_P ( C ), Periodontitis ( D ), and Control ( E ) groups. The sections were subjected to immunohistochemistry for the detection of IRS-2 (brown-yellow color) and counterstained with hematoxylin. Arrows: inflammatory cells; Fb: fibroblasts; BV: blood vessel. Scale bars: 20 µm. Figure ( F ): number of IRS-2-immunolabelled cells in the lamina propria of human gingiva biopsies.

    Article Snippet: The samples were incubated overnight with the rabbit primary antibody against IRS-2 (AB Clonal—A7945, Woburn, MA, USA), following the manufacturer’s instructions, at a concentration of 1:150.

    Techniques: Immunohistochemistry, Control